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1.
Diacylglycerol acyltransferase-1 inhibition enhances intestinal fatty acid oxidation and reduces energy intake in rats.
J Lipid Res;
54(5): 1369-84, 2013 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-23449193
2.
Intestinal DGAT1 deficiency reduces postprandial triglyceride and retinyl ester excursions by inhibiting chylomicron secretion and delaying gastric emptying.
J Lipid Res;
53(11): 2364-79, 2012 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-22911105
3.
Identification, optimisation and in vivo evaluation of oxadiazole DGAT-1 inhibitors for the treatment of obesity and diabetes.
Bioorg Med Chem Lett;
22(12): 3873-8, 2012 Jun 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-22608962
4.
Selective antagonism of the NPY Y5 receptor does not have a major effect on feeding in rats.
Diabetes;
51(8): 2441-9, 2002 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-12145156
5.
Proopiomelanocortin-derived peptides in rat cerebrospinal fluid and hypothalamic extracts: evidence that secretion is regulated with respect to energy balance.
Endocrinology;
144(3): 760-6, 2003 Mar.
Artículo
en Inglés
| MEDLINE | ID: mdl-12586751
6.
Design and optimization of pyrazinecarboxamide-based inhibitors of diacylglycerol acyltransferase 1 (DGAT1) leading to a clinical candidate dimethylpyrazinecarboxamide phenylcyclohexylacetic acid (AZD7687).
J Med Chem;
55(23): 10610-29, 2012 Dec 13.
Artículo
en Inglés
| MEDLINE | ID: mdl-23116186
7.
Discovery of a potent, selective, and orally efficacious pyrimidinooxazinyl bicyclooctaneacetic acid diacylglycerol acyltransferase-1 inhibitor.
J Med Chem;
52(6): 1558-68, 2009 Mar 26.
Artículo
en Inglés
| MEDLINE | ID: mdl-19256504
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